Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464508 | 0.83 | MAOA (0.51) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL20147143 | 0.80 | DYRK1A (0.41) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL4166593 | 0.76 | HASPIN (0.52) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL12464614 | 0.76 | MAPT (0.64) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL20135890 | 0.72 | AKR1C3 (0.53) | KDM4EMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL12464506 | 0.70 | MAOA (0.49) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL24277027 | 0.69 | MAOA (0.48) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL20135910 | 0.68 | LMNA (0.56) | ACHEKDM4EMAPTMEN1KMT2A | |
| SCHEMBL1921708 | 0.68 | HASPIN (0.61) | MAOAMAOBHASPINCHUKACHE | |
| SCHEMBL4176158 | 0.68 | HASPIN (0.48) | MAOAMAOBHASPINCHUKACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321264-A1 | SELECTIVE INHIBITORS OF GENOTOXIC STRESS-INDUCED IKK/NF-KB PATHWAYS | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (DE) | 2018-05-16 | — | — | EP | disclosed |