Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482566 | 0.95 | TSHR (0.35) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL23930358 | 0.93 | TSHR (0.40) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL29012022 | 0.93 | TSHR (0.40) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL28431829 | 0.93 | TSHR (0.40) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL6303628 | 0.93 | TSHR (0.40) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL3481794 | 0.90 | LMNA (0.30) | TSHR | |
| SCHEMBL3481448 | 0.85 | LMNA (0.30) | TSHR | |
| SCHEMBL613245 | 0.85 | TSHR (0.39) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL6057116 | 0.82 | TSHR (0.44) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL2120675 | 0.82 | TSHR (0.44) | FDPSSMPD1TSHRTHRBGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142558-B1 | HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-10-05 | — | — | EP | disclosed |
| EP-2137198-B1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-05-18 | — | — | EP | disclosed |
| EP-2160424-B1 | CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8088940-B2 | Having an organofunctional group bonded to a silicon atom through a stable bridging group that is able to react with an organic resin (2,2,4,4,6-pentamethyl-[1,3,2]dioxasilinane); enhanced storage stability, adhesion strength, durability, filler dispersibility, tensile strength, elongation, tear strength | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| EP-2160424-A1 | CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE | Momentive Performance Materials Inc. (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-2137198-A1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | Momentive Performance Materials Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| US-7569645-B2 | Curable silyl-containing polymer composition containing paint adhesion additive | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-08-04 | — | — | US | disclosed |
| WO-2009005642-A1 | CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-01-08 | — | — | WO | disclosed |
| US-20090005498-A1 | Curable silyl-containing polymer composition containing paint adhesion additive | MOMENTIVE PERFORMANCE MATERIALS INC. | 2009-01-01 | — | — | US | disclosed |
| US-20080237537-A1 | Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-10-02 | — | — | US | disclosed |
| WO-2008112150-A1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-09-18 | — | — | WO | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080237537-A1 | Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same | GSTM1, GSTP1, GSTM2 | FDPS 1422/4885SMPD1 1329/4885TSHR 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.