SCHEMBL20148112

SCHEMBL20148112

Cc1ccc(OCCOc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.72
ALDH1A1 P00352 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
MAPK1 P28482 2/20 0.64
TSHR P16473 2/20 0.64
TP53 P04637 1/20 0.64
PLA2G4B P0C869 3/20 0.62
NPC1 O15118 1/20 0.60
USP2 O75604 1/20 0.60
ALOX15 P16050 1/20 0.60
HSD17B10 Q99714 1/20 0.60
RARB P10826 4/20 0.59
SRD5A2 P31213 1/20 0.59
HTT P42858 1/20 0.58
MAPT P10636 1/20 0.56
PLA2G4A P47712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196110 0.90 PKM (0.88) PKMALDH1A1L3MBTL1MAPK1TSHR
SCHEMBL14967104 0.88 PKM (0.57) PKMALDH1A1SMN1; SMN2L3MBTL1MAPK1
SCHEMBL9044645 0.85 L3MBTL1 (0.61) PKML3MBTL1NPC1MAPT
SCHEMBL11111198 0.85 STAT3 (0.59) PKMALDH1A1SMN1; SMN2L3MBTL1MAPK1
SCHEMBL18477942 0.85 L3MBTL1 (0.75) PKMALDH1A1SMN1; SMN2L3MBTL1MAPK1
SCHEMBL2741522 0.85 PKM (0.72) PKMALDH1A1SMN1; SMN2L3MBTL1MAPK1
SCHEMBL10495065 0.84 NPC1 (0.88) ALDH1A1SMN1; SMN2MAPK1TSHRTP53
SCHEMBL1285278 0.84 PKM (1.00) PKMALDH1A1L3MBTL1MAPK1TSHR
SCHEMBL4509186 0.84 PKM (0.78) PKMALDH1A1L3MBTL1MAPK1TSHR
SCHEMBL20502046 0.84 PKM (0.78) PKMALDH1A1L3MBTL1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134025-A1 METAL-CLAD LAMINATE SHEET MANUFACTURING METHOD, AND METAL-CLAD LAMINATE SHEET USING THE SAME KURARAY CO., LTD. (JP) 2018-05-17 US disclosed