SCHEMBL2741522

SCHEMBL2741522

COCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.72
MAPK1 P28482 2/20 0.64
TSHR P16473 2/20 0.64
TP53 P04637 1/20 0.64
PLA2G4B P0C869 4/20 0.62
MAPT P10636 2/20 0.61
USP2 O75604 1/20 0.60
ALOX15 P16050 1/20 0.60
HSD17B10 Q99714 1/20 0.60
RARB P10826 4/20 0.59
RAB9A P51151 2/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
HTT P42858 1/20 0.58
NPC1 O15118 1/20 0.57
POLB P06746 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ALDH1A1 P00352 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
PLA2G4A P47712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13861910 0.95 RARB (0.68) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL9361418 0.95 RARB (0.68) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL13448825 0.95 RARB (0.68) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL15562010 0.95 RARB (0.68) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL9019628 0.95 RARB (0.68) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL2882011 0.91 PLA2G4B (0.70) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL196110 0.90 PKM (0.88) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL6132822 0.89 TP53 (0.75) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL6132656 0.89 TP53 (0.75) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL18682480 0.89 TP53 (0.75) PKMMAPK1TSHRTP53PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 US disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 US disclosed
CN-111936471-B Non-fused thiophene derivatives and uses thereof 埃尼奥制药公司 2024-10-29 CN disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 US disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 EP disclosed
US-11840527-B2 Non-fused thiophene derivatives and their uses ENYO PHARMA (FR) 2023-12-12 US disclosed
US-11767316-B2 Non-fused thiophene derivatives and their uses ENYO PHARMA (FR) 2023-09-26 US disclosed
CN-111386118-B Combination pharmaceutical agents as RSV inhibitors 英安塔制药有限公司 2023-05-09 CN disclosed
EP-1670805-A1 THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS F. HOFFMANN-LA ROCHE AG (CH) 2006-06-21 EP disclosed
US-20050072963-A1 Liquid crystal compounds QINETIQ LIMITED (GB) 2005-04-07 US disclosed
WO-2005028484-A1 THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS F. HOFFMANN-LA ROCHE AG (CH) 2005-03-31 WO disclosed
US-20050065151-A1 Thiazolopyridine HOFFMANN-LA ROCHE INC. 2005-03-24 US disclosed
EP-1470105-A1 LIQUID CRYSTAL COMPOUNDS Qinetiq Limited (GB) 2004-10-27 EP disclosed
WO-2003064381-A1 LIQUID CRYSTAL COMPOUNDS QINETIQ LIMITED (GB) 2003-08-07 WO disclosed
US-20020111369-A1 Aryl sulfonic acids and derivatives as FSH antagonists AMERICAN HOME PRODUCTS CORPORATION (US) 2002-08-15 US disclosed
US-6355633-B1 CONTRACEPTIVES AMERICAN HOME PRODUCTS CORPORATION 2002-03-12 US disclosed
WO-2000058277-A1 ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-10-05 WO disclosed
US-4009208-A N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) STERLING DRUG INC. (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 PKM 625/4885MAPK1 2860/4885TSHR 1396/4885
US-20050072963-A1 Liquid crystal compounds C1S, SCO2, F12 PKM 2607/4885MAPK1 2134/4885TSHR 2862/4885
US-20050065151-A1 Thiazolopyridine ADORA2A, ADORA3, ADORA1 PKM 1839/4885MAPK1 3067/4885TSHR 78/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 PKM 625/4885MAPK1 2860/4885TSHR 1396/4885
US-11767316-B2 Non-fused thiophene derivatives and their uses FTH1, SLC40A1, FECH PKM 769/4885MAPK1 4572/4885TSHR 1240/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 PKM 625/4885MAPK1 2860/4885TSHR 1396/4885
US-20020111369-A1 Aryl sulfonic acids and derivatives as FSH antagonists FSHR, GNRHR, LHCGR PKM 4553/4885MAPK1 1934/4885TSHR 29/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 PKM 3237/4885MAPK1 1820/4885TSHR 4229/4885
US-11840527-B2 Non-fused thiophene derivatives and their uses FTH1, SLC40A1, FECH PKM 769/4885MAPK1 4572/4885TSHR 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.