Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398099 | 1.00 | POLB (0.44) | POLBSMN1; SMN2LMNAL3MBTL1RAB9A | |
| SCHEMBL4398103 | 1.00 | POLB (0.44) | POLBSMN1; SMN2LMNAL3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL28114698 | 0.98 | POLB (0.43) | POLBSMN1; SMN2LMNAL3MBTL1RAB9A | |
| SCHEMBL19779833 | 0.85 | ACHE (0.43) | POLBSMN1; SMN2LMNANFE2L2ALDH1A1 | |
| SCHEMBL19900300 | 0.85 | MAOB (0.43) | POLBSMN1; SMN2LMNAL3MBTL1RAB9A | |
| SCHEMBL5771963 | 0.85 | NFE2L2 (0.35) | POLBSMN1; SMN2LMNAL3MBTL1RAB9A | |
| SCHEMBL5771965 | 0.85 | NFE2L2 (0.35) | POLBSMN1; SMN2LMNAL3MBTL1RAB9A | |
| SCHEMBL5302952 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2LMNARAB9AALDH1A1MEN1 | |
| SCHEMBL19900073 | 0.85 | ACHE (0.43) | POLBSMN1; SMN2LMNANFE2L2ALDH1A1 | |
| SCHEMBL2164318 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2LMNARAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | FORUM PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | CHRNA7, CHRNA5, CHRNA2 | POLB 2398/4885SMN1; SMN2 971/4885LMNA 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.