Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 6/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148977 | 0.83 | RORC (0.46) | TACR1RORCNR1I2 | |
| SCHEMBL28017037 | 0.77 | RORC (0.47) | RORCNR1I2 | |
| SCHEMBL20149028 | 0.74 | KDM1A (0.45) | TACR1KDM1AHTR2CSLC6A2HTR2A | |
| SCHEMBL20149036 | 0.74 | KDM1A (0.45) | TACR1KDM1AHTR2CSLC6A2HTR2A | |
| SCHEMBL20149098 | 0.71 | KDM1A (0.48) | KDM1AHTR2CHTR2AKCNH2PRCP | |
| SCHEMBL20139890 | 0.71 | RORC (0.61) | RORCNR1I2 | |
| SCHEMBL16031350 | 0.71 | KDM1A (0.45) | TACR1KDM1AHTR2CSLC6A2HTR2A | |
| SCHEMBL2146399 | 0.71 | KDM1A (0.45) | TACR1KDM1AHTR2CSLC6A2HTR2A | |
| SCHEMBL2146401 | 0.71 | KDM1A (0.45) | TACR1KDM1AHTR2CSLC6A2HTR2A | |
| SCHEMBL16031353 | 0.71 | KDM1A (0.45) | TACR1KDM1AHTR2CSLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |