Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149045 | 0.82 | SLC6A2 (0.40) | KDM1AROCK2HTR2CHTR2AHTR1A | |
| SCHEMBL8660684 | 0.77 | MAOA (0.55) | KDM1AMAOBMAOAHTR2CKCNH2 | |
| SCHEMBL3870077 | 0.77 | MAOA (0.55) | KDM1AMAOBMAOAHTR2CKCNH2 | |
| SCHEMBL3870080 | 0.77 | MAOA (0.55) | KDM1AMAOBMAOAHTR2CKCNH2 | |
| SCHEMBL20149028 | 0.77 | KDM1A (0.45) | KDM1AMAOBHTR2CHTR2AKCNH2 | |
| SCHEMBL20149036 | 0.77 | KDM1A (0.45) | KDM1AMAOBHTR2CHTR2AKCNH2 | |
| SCHEMBL24990313 | 0.76 | CHRNB2 (0.46) | KDM1AHTR2CHTR2AKCNH2 | |
| SCHEMBL16032314 | 0.76 | SLC6A2 (0.44) | KDM1AROCK2HTR2CHTR2AHTR1A | |
| SCHEMBL16032316 | 0.76 | SLC6A2 (0.44) | KDM1AROCK2HTR2CHTR2AHTR1A | |
| SCHEMBL16032313 | 0.76 | SLC6A2 (0.44) | KDM1AROCK2HTR2CHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |