Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149260 | 0.87 | RORC (0.54) | RORCNR1I2NR1H3NR1H2 | |
| SCHEMBL20148986 | 0.83 | TACR1 (0.42) | RORCNR1I2TACR1 | |
| SCHEMBL20149019 | 0.79 | RORC (0.57) | RORCNR1I2NR1H3NR1H2 | |
| SCHEMBL8021367 | 0.78 | NR1H2 (0.58) | RORCNR1I2NR1H3NR1H2 | |
| SCHEMBL20148982 | 0.78 | RORC (0.50) | RORCNR1I2NR1H3NR1H2 | |
| SCHEMBL20149268 | 0.75 | RORC (0.50) | RORCNR1I2TACR1 | |
| SCHEMBL20139587 | 0.75 | RORC (0.57) | RORCNR1I2NR1H3NR1H2 | |
| Hydrochloric Acid SCHEMBL23683624 | 0.74 | RORC (0.56) | RORCNR1I2NR1H3NR1H2 | |
| SCHEMBL20148964 | 0.73 | RORC (0.80) | RORCNR1I2 | |
| SCHEMBL20139578 | 0.73 | RORC (0.80) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |