Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149098 | 0.82 | KDM1A (0.48) | KDM1AROCK2HTR2CHTR1AHTR2A | |
| SCHEMBL13615034 | 0.79 | TTR (0.56) | NOS1NOS2TTR | |
| SCHEMBL23683586 | 0.76 | RORC (0.56) | TTRRORC | |
| SCHEMBL20149049 | 0.76 | RORC (0.56) | TTRRORC | |
| Hydrochloric Acid SCHEMBL23683617 | 0.75 | RORC (0.55) | TTRRORC | |
| Hydrochloric Acid SCHEMBL23683618 | 0.75 | RORC (0.55) | TTRRORC | |
| SCHEMBL20149028 | 0.74 | KDM1A (0.45) | SLC6A2SLC6A4SLC6A3KDM1AHTR2C | |
| SCHEMBL20149036 | 0.74 | KDM1A (0.45) | SLC6A2SLC6A4SLC6A3KDM1AHTR2C | |
| SCHEMBL23683613 | 0.72 | RORC (0.59) | RORCHTR2CHTR2A | |
| SCHEMBL20139668 | 0.72 | RORC (0.59) | RORCHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |