Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 7/20 | 0.38 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | CTSE | P14091 | 2/20 | 0.38 |
| ▸ | PGC | P20142 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23683586 | 1.00 | RORC (0.56) | RORCGBA1CCR5RENCTSD | |
| Hydrochloric Acid SCHEMBL23683618 | 0.99 | RORC (0.55) | RORCGBA1CCR5RENCTSD | |
| Hydrochloric Acid SCHEMBL23683617 | 0.99 | RORC (0.55) | RORCGBA1CCR5RENCTSD | |
| SCHEMBL23683598 | 0.81 | RORC (0.59) | RORC | |
| SCHEMBL20139668 | 0.81 | RORC (0.59) | RORC | |
| SCHEMBL23683613 | 0.81 | RORC (0.59) | RORC | |
| Hydrochloric Acid SCHEMBL16032992 | 0.81 | GBA1 (0.56) | RORCGBA1CCR5RENCTSD | |
| SCHEMBL20139701 | 0.77 | RORC (0.65) | RORCGBA1CCR5 | |
| SCHEMBL20149045 | 0.76 | SLC6A2 (0.40) | RORCTTR | |
| SCHEMBL20139587 | 0.74 | RORC (0.57) | RORCGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078186-B2 | ROR γ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-08-03 | — | — | US | disclosed |
| US-11078186-B2 | ROR γ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-08-03 | — | — | US | disclosed |
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078186-B2 | ROR γ modulators | RORB, RORC, RORA | RORC 2/4885GBA1 1704/4885CCR5 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.