Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.71 |
| ▸ | TACR1 | P25103 | 9/20 | 0.47 |
| ▸ | TACR2 | P21452 | 4/20 | 0.47 |
| ▸ | TACR3 | P29371 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TAC3 | Q9UHF0 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713149 | 0.83 | RORC (1.00) | RORCTACR1TACR2TACR3CYP3A4 | |
| SCHEMBL23713009 | 0.75 | RORC (1.00) | RORC | |
| SCHEMBL20149048 | 0.73 | RORC (0.77) | RORCTACR3 | |
| SCHEMBL20149105 | 0.69 | RORC (1.00) | RORC | |
| SCHEMBL20002952 | 0.69 | RORC (0.47) | RORCPAX8 | |
| SCHEMBL20149050 | 0.69 | RORC (0.84) | RORCTACR1TACR2 | |
| SCHEMBL20149129 | 0.69 | RORC (0.80) | RORCTACR1TACR2CYP3A4CYP2D6 | |
| SCHEMBL23713056 | 0.69 | RORC (1.00) | RORCTACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15751783 | 0.69 | TACR1 (0.70) | RORCTACR1TACR2TACR3TAC3 | |
| SCHEMBL17086647 | 0.68 | TACR1 (0.46) | RORCTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |