Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141024 | 0.87 | ACHE (0.52) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL22691294 | 0.86 | LMNA (0.45) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL27357778 | 0.85 | ACHE (0.47) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL27357775 | 0.85 | ACHE (0.47) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL26460411 | 0.85 | ACHE (0.47) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL25457968 | 0.84 | MEN1 (0.44) | ACHELMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22423305 | 0.84 | MEN1 (0.44) | ACHELMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24854772 | 0.84 | ACHE (0.50) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL24990592 | 0.82 | L3MBTL1 (0.44) | L3MBTL1ACHELMNASMN1; SMN2KMT2A | |
| SCHEMBL26551992 | 0.82 | KMT2A (0.45) | L3MBTL1ACHELMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |
| WO-2018089373-A9 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018089373-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |