SCHEMBL20149447

SCHEMBL20149447

c1ccc(-n2c3ccccc3c3cccc(-c4cccc5c6ccccc6n(-c6cc7ccccc7c7ccccc67)c45)c32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
DUSP3 P51452 1/20 0.40
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 3/20 0.36
TSHR P16473 2/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
IL1R1 P14778 1/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20149457 0.93 DUSP3 (0.44) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL20706850 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL17228248 0.90 L3MBTL1 (0.52) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20149472 0.89 L3MBTL1 (0.40) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL20149453 0.89 L3MBTL1 (0.40) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL20149451 0.87 L3MBTL1 (0.44) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL20706789 0.87 L3MBTL1 (0.44) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL20706844 0.84 L3MBTL1 (0.65) L3MBTL1KDM4EATMDUSP3CYP1A2
SCHEMBL27864606 0.84 L3MBTL1 (0.46) L3MBTL1KDM4EATMDUSP3ALDH1A1
SCHEMBL30017427 0.84 L3MBTL1 (0.65) L3MBTL1KDM4EATMDUSP3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230023388-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20220173326-A1 MELT MIXTURE FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-02 US disclosed
US-10622570-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-14 US disclosed
US-20190088883-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2019-03-21 US disclosed
EP-3439058-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2019-02-06 EP disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10622570-B2 Organic electroluminescent element NR2E3, ESR1, NCOR2 L3MBTL1 1849/4885KDM4E 406/4885ATM 4041/4885
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, LAGE3, KCNN4 L3MBTL1 157/4885KDM4E 846/4885ATM 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.