SCHEMBL20149451

SCHEMBL20149451

c1ccc(-n2c3ccccc3c3ccc(-c4cccc5c6ccccc6n(-c6cc7ccccc7c7ccccc67)c45)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
DUSP3 P51452 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
IL1R1 P14778 1/20 0.33
ALDH1A1 P00352 5/20 0.33
KMT2A Q03164 3/20 0.33
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 2/20 0.31
RXFP1 Q9HBX9 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20149453 0.96 L3MBTL1 (0.40) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20706789 0.93 L3MBTL1 (0.44) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20149464 0.92 CYP1A2 (0.38) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20149472 0.89 L3MBTL1 (0.40) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20149459 0.88 KDM4E (0.46) L3MBTL1KDM4EATMCYP2C9CYP2C19
SCHEMBL15480218 0.87 L3MBTL1 (0.51) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20149447 0.87 L3MBTL1 (0.47) L3MBTL1KDM4EATMCYP1A2CYP2C9
SCHEMBL20821707 0.87 L3MBTL1 (0.55) L3MBTL1KDM4EATMDUSP3IL1R1
SCHEMBL22751024 0.86 TDP2 (0.37) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL15435979 0.84 L3MBTL1 (0.51) L3MBTL1KDM4EATMDUSP3IL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230023388-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20220173326-A1 MELT MIXTURE FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-02 US disclosed
US-10622570-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-14 US disclosed
US-20190088883-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2019-03-21 US disclosed
EP-3439058-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2019-02-06 EP disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10622570-B2 Organic electroluminescent element NR2E3, ESR1, NCOR2 L3MBTL1 1849/4885KDM4E 406/4885ATM 4041/4885
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, LAGE3, KCNN4 L3MBTL1 157/4885KDM4E 846/4885ATM 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.