SCHEMBL20149461

SCHEMBL20149461

c1ccc2cc(-n3c4ccccc4c4ccc(-c5cccc6c7ccccc7n(-c7ccc8ccccc8c7)c56)cc43)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 8/20 0.39
MAPK9 P45984 6/20 0.39
DUSP3 P51452 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPK8 P45983 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36
TUBB6 Q9BUF5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20149462 0.96 KDM4E (0.44) MAPK10MAPK9DUSP3KDM4EATM
SCHEMBL20149460 0.96 KDM4E (0.44) MAPK10MAPK9DUSP3KDM4EATM
SCHEMBL27049772 0.92 DUSP3 (0.37) MAPK10MAPK9DUSP3KDM4EATM
SCHEMBL20706672 0.90 KDM4E (0.38) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL20821639 0.89 SIRT2 (0.33) MAPK10MAPK9DUSP3KDM4EMAPK8
SCHEMBL20149470 0.89 KDM4E (0.44) MAPK10MAPK9DUSP3KDM4EATM
SCHEMBL20821621 0.89 KDM4E (0.44) MAPK10MAPK9DUSP3KDM4EATM
SCHEMBL18958111 0.88 MAPK10 (0.38) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL17349136 0.88 MAPK10 (0.38) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL17349279 0.88 MAPK10 (0.38) MAPK10MAPK9KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230023388-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20220173326-A1 MELT MIXTURE FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-02 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, LAGE3, KCNN4 MAPK10 4274/4885MAPK9 3177/4885DUSP3 3064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.