SCHEMBL20149470

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20821621	1.00	KDM4E (0.44)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL27049773	0.96	KDM4E (0.40)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL27049772	0.96	DUSP3 (0.37)	KDM4EATML3MBTL1DUSP3HPGD
	SCHEMBL25940843	0.95	KDM4E (0.42)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL22483479	0.94	KDM4E (0.38)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL20706672	0.93	KDM4E (0.38)	KDM4EATML3MBTL1PTGER4HPGD
	SCHEMBL21578617	0.93	KDM4E (0.37)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL25941744	0.93	KDM4E (0.40)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL21578614	0.93	KDM4E (0.37)	KDM4EATML3MBTL1PTGER4DUSP3
	SCHEMBL20149462	0.93	KDM4E (0.44)	KDM4EATML3MBTL1DUSP3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.