SCHEMBL22483479

SCHEMBL22483479

c1ccc(-c2cccc(-n3c4ccccc4c4cccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6ccccc6c5)c43)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDE10A Q9Y233 1/20 0.37
NR3C1 P04150 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
TSPO P30536 2/20 0.34
PDE6D O43924 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
DUSP3 P51452 1/20 0.33
PTGER4 P35408 1/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21578614 0.99 KDM4E (0.37) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL21578617 0.99 KDM4E (0.37) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL25940956 0.98 KDM4E (0.38) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL25941744 0.97 KDM4E (0.40) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL27049773 0.95 KDM4E (0.40) KDM4EATML3MBTL1NR3C1HSD17B1
SCHEMBL20706672 0.95 KDM4E (0.38) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL21578615 0.94 KDM4E (0.34) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL25941031 0.94 KDM4E (0.40) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL25940843 0.94 KDM4E (0.42) KDM4EATML3MBTL1PDE10ANR3C1
SCHEMBL20149470 0.94 KDM4E (0.44) KDM4EATML3MBTL1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 US disclosed
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 US disclosed
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-20230209856-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209856-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, L3MBTL4, PIEZO1 KDM4E 2192/4885ATM 2223/4885L3MBTL1 24/4885
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, LEF1 KDM4E 2520/4885ATM 2804/4885L3MBTL1 514/4885
US-11760769-B2 Composition and organic light-emitting device including the same CRY1, CRY2, LEF1 KDM4E 2520/4885ATM 2804/4885L3MBTL1 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.