Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654446 | 0.82 | RXRA (0.47) | GAARXRARXRBRXRGALDH1A1 | |
| Hydrochloric Acid SCHEMBL17580966 | 0.81 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HSD11B1SCN9APOLB | |
| SCHEMBL1840269 | 0.78 | SCN9A (0.43) | ALDH1A1L3MBTL1HSD11B1SCN9APOLB | |
| SCHEMBL24027308 | 0.76 | KCNH2 (0.37) | ALDH1A1KDM4E | |
| SCHEMBL7701143 | 0.75 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HSD11B1SCN9APOLB | |
| SCHEMBL255271 | 0.73 | EPHX2 (0.43) | GAARXRARXRBRXRGALDH1A1 | |
| SCHEMBL29635691 | 0.73 | EPHX2 (0.43) | GAARXRARXRBRXRGALDH1A1 | |
| SCHEMBL9242571 | 0.73 | HSD11B1 (0.53) | GAARXRARXRBRXRGALDH1A1 | |
| SCHEMBL364380 | 0.73 | GAA (0.42) | GAARXRARXRBRXRGALDH1A1 | |
| SCHEMBL12473634 | 0.73 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HSD11B1SCN9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |