Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407980 | 1.00 | PRMT6 (0.51) | PRMT6ADORA1ADORA3LMNAADORA2A | |
| SCHEMBL20149845 | 0.93 | PRMT6 (0.51) | PRMT6ADORA1P2RY12 | |
| SCHEMBL18464846 | 0.92 | PRMT6 (0.53) | PRMT6ADORA1ADORA3LMNAADORA2A | |
| SCHEMBL26553789 | 0.92 | PRMT6 (0.53) | PRMT6ADORA1ADORA3LMNAADORA2A | |
| SCHEMBL38653713 | 0.92 | ADORA1 (0.56) | ADORA1ADORA3LMNAADORA2AADORA2B | |
| SCHEMBL19407591 | 0.92 | ADORA1 (0.56) | ADORA1ADORA3LMNAADORA2AADORA2B | |
| SCHEMBL7064875 | 0.92 | ADORA1 (0.56) | ADORA1ADORA3LMNAADORA2AADORA2B | |
| SCHEMBL7064871 | 0.92 | ADORA1 (0.56) | ADORA1ADORA3LMNAADORA2AADORA2B | |
| SCHEMBL25966158 | 0.91 | PRMT6 (0.52) | PRMT6ADORA1ADORA3LMNAADORA2A | |
| SCHEMBL25966132 | 0.90 | PRMT6 (0.50) | PRMT6ADORA1ADORA3LMNAADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250125-A1 | NUCLEIC ACID POLYMERS | JANSSEN BIOPHARMA, LLC | 2023-08-10 | — | — | US | disclosed |
| US-20230203078-A1 | SYNTHESIS OF 3'N NUCLEOSIDES THROUGH OXIME INTERMEDIATES AND RELATED COMPOUNDS | Janssen Biopharma, Inc. | 2023-06-29 | — | — | US | disclosed |
| US-20180135054-A1 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE | ALIOS BIOPHARMA, INC. (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203078-A1 | SYNTHESIS OF 3'N NUCLEOSIDES THROUGH OXIME INTERMEDIATES AND RELATED COMPOUNDS | NT5C3B, PNP, NME1 | PRMT6 289/4885ADORA1 750/4885ADORA3 349/4885 |
| US-20180135054-A1 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE | NSUN2, ADAR, POLM | PRMT6 597/4885ADORA1 2193/4885ADORA3 985/4885 |
| US-20230250125-A1 | NUCLEIC ACID POLYMERS | NSUN2, NSUN3, RNGTT | PRMT6 606/4885ADORA1 3343/4885ADORA3 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.