Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 7/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137405 | 0.90 | BCL2A1 (0.38) | BCHENR1D1ACHEALDH1A1MEN1 | |
| SCHEMBL20151842 | 0.89 | PPARD (0.36) | TSPOPPARAHDAC8L3MBTL1POLB | |
| SCHEMBL20151838 | 0.88 | PPARG (0.39) | TSPOBCHEACHEL3MBTL1KDM4E | |
| SCHEMBL20137411 | 0.88 | LTB4R2 (0.40) | BCHENR1D1POLB | |
| SCHEMBL25802749 | 0.81 | TSPO (0.46) | TSPOBCHEPPARAHDAC8NR1D1 | |
| SCHEMBL20151851 | 0.79 | PPARD (0.33) | NR1D1KDM4E | |
| SCHEMBL20137115 | 0.79 | LTB4R2 (0.44) | BCHEACHE | |
| SCHEMBL20137037 | 0.77 | KDM4E (0.38) | PPARAPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL20151854 | 0.77 | NR1D1 (0.39) | BCHENR1D1ALDH1A1HTT | |
| SCHEMBL20151846 | 0.76 | PPARD (0.38) | PPARAL3MBTL1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691975-B2 | MAGL inhibitors | H. LUNDBECKA/S (DK) | 2023-07-04 | — | — | US | disclosed |
| US-9981930-B1 | MAGL inhibitors | ABIDE THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20180134675-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691975-B2 | MAGL inhibitors | MAG, MAGI3, MGLL | TSPO 3919/4885BCHE 1581/4885PPARA 1470/4885 |
| US-20180134675-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | TSPO 3700/4885BCHE 1310/4885PPARA 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.