SCHEMBL20151073

SCHEMBL20151073

N=CN/N=C/c1ccc(/C=N/NC(=N)N)o1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 5/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
KDM4E B2RXH2 4/20 0.41
LMNA P02545 4/20 0.41
CYP3A4 P08684 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 1/20 0.41
HIF1A Q16665 1/20 0.41
TP53 P04637 1/20 0.41
PDE3A Q14432 1/20 0.41
SARM1 Q6SZW1 1/20 0.41
NPSR1 Q6W5P4 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
PRMT5 O14744 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20148187 0.90 ALDH1A1 (0.53) MAPTMAPK1ALDH1A1GAAMEN1
SCHEMBL8974177 0.77 MAPT (0.63) MAPTMAPK1ALDH1A1GAAMEN1
SCHEMBL20150970 0.77 KDM4E (0.33) MAPTMEN1KMT2AKDM4EPOLB
SCHEMBL21908577 0.77 L3MBTL1 (0.38) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL20151064 0.77 GAA (0.31) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL20150963 0.76 POLB (0.57) MEN1KMT2AKDM4ELMNAPOLB
SCHEMBL20150968 0.75 CTH (0.40) MAPTMEN1KMT2AKDM4ELMNA
SCHEMBL20151076 0.74 KDM4E (0.33) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL20150967 0.74 GAA (0.35) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL10054978 0.73 KDM4E (0.63) MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067860-A1 COMPOSITIONS AND METHODS FOR CARBON DIOXIDE SOLIDIFICATION CHEVRON U.S.A. INC. 2024-02-29 US disclosed
US-10633332-B2 Guanidine compounds for removal of oxyanions from aqueous solutions and for carbon dioxide capture UT-BATTELLE, LLC (US) 2020-04-28 US disclosed
US-20180134655-A1 GUANIDINE COMPOUNDS FOR REMOVAL OF OXYANIONS FROM AQUEOUS SOLUTIONS AND FOR CARBON DIOXIDE CAPTURE U.S. DEPARTMENT OF ENERGY 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10633332-B2 Guanidine compounds for removal of oxyanions from aqueous solutions and for carbon dioxide capture GUCY1A1, GUCY1A2, GUCY1B1 MAPT 2656/4885MAPK1 670/4885ALDH1A1 2485/4885
US-20180134655-A1 GUANIDINE COMPOUNDS FOR REMOVAL OF OXYANIONS FROM AQUEOUS SOLUTIONS AND FOR CARBON DIOXIDE CAPTURE GUCY1A1, GUCY1A2, GUCY1B1 MAPT 2656/4885MAPK1 670/4885ALDH1A1 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.