Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951947 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL5734790 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL419596 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL29249202 | 0.83 | ACHE (0.60) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL13807149 | 0.82 | ACHE (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL17320187 | 0.82 | ACHE (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL12257883 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL27460529 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL32670810 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL11871188 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TSHRKDM4ETDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4707264-A2 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | Verbio SE (DE) | 2026-03-11 | — | — | EP | disclosed |
| EP-4122924-B1 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | VERBIO SE (DE) | 2025-11-19 | — | — | EP | disclosed |
| CN-118459478-B | BRD4 protein targeted degradation agent and preparation method and application thereof | 深圳大学 | 2024-10-29 | — | — | CN | disclosed |
| US-12065450-B2 | Compounds and the use thereof in metathesis reactions | VERBIO SE (DE) | 2024-08-20 | — | — | US | disclosed |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
| CN-117800921-B | Imidazolidine diketone HDAC inhibitor, preparation method and application | 南京市鸿舜医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117800921-A | Imidazolidine diketone HDAC inhibitor, preparation method and application | 南京市鸿舜医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-113286792-B | N-chromen-4-one containing derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-11780814-B2 | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death | ALONBIO LTD. (IL) | 2023-10-10 | — | — | US | disclosed |
| US-20230265087-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint, Inc. | 2023-08-24 | — | — | US | disclosed |
| US-4999448-A | ALKYLATION WITH PHENYLTHIOMETHYL LITHIUM COMPOUND, CYCLIZATION, INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0403026-A1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DowElanco (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |
| US-4457810-A | ANODIC OXIDATION OF DI-P-TOLYL ETHER IN PRESENCE OF METHANOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0054698-B1 | 4,4'-DIPHENYL ETHER-DIALDEHYDE-BIS-DIMETHYL ACETAL, AND A METHOD FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-20 | — | — | EP | disclosed |
| US-4444567-A | ALKOXY BENZALDEHYDES, ALKOXY BENZOATES | PHILLIPS PETROLEUM COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| US-4405816-A | INTERMEDIATES FOR POLYETHERS AND LIGHT SEN ITIVE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| EP-0054698-A1 | 4,4'-Diphenyl ether-dialdehyde-bis-dimethyl acetal, and a method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12065450-B2 | Compounds and the use thereof in metathesis reactions | PRMT6, CYP2D6, POR | ALDH1A1 1286/4885TSHR 1953/4885KDM4E 2310/4885 |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | ALDH1A1 2871/4885TSHR 4424/4885KDM4E 3110/4885 |
| US-20230265087-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | TIE1, TEK, KDR | ALDH1A1 3772/4885TSHR 2258/4885KDM4E 2036/4885 |
| US-11780814-B2 | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death | CCL2, CXCR2, CCL5 | ALDH1A1 1330/4885TSHR 2468/4885KDM4E 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.