Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20151895 | 0.95 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL25603214 | 0.84 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL25969880 | 0.83 | MAPT (0.43) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL18122193 | 0.77 | TOP2A (0.56) | SMN1; SMN2HPGDHTTTOP2AIDO1 | |
| SCHEMBL22473980 | 0.75 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2HPGDCASP1MPI | |
| SCHEMBL18272794 | 0.74 | TTR (0.49) | ALDH1A1HPGDMAPTTOP2AIDO1 | |
| SCHEMBL20693320 | 0.72 | SLC9A1 (0.38) | ALDH1A1SMN1; SMN2HPGDHTTTP53 | |
| SCHEMBL16980287 | 0.72 | CHRM2 (0.34) | ALDH1A1IDO1TDO2DRD2HTR6 | |
| SCHEMBL25890747 | 0.72 | TDO2 (0.38) | ALDH1A1SMN1; SMN2HPGDHTTIDO1 | |
| SCHEMBL27112668 | 0.71 | TOP2A (0.36) | ALDH1A1SMN1; SMN2HPGDHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133340-A1 | ANTIBODY-DRUG CONJUGATES | CHO Pharma Inc. (TW) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133340-A1 | ANTIBODY-DRUG CONJUGATES | CSGALNACT1, ST6GAL1, PA2G4 | ALDH1A1 303/4885SMN1; SMN2 1622/4885HPGD 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.