Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 9/20 | 0.41 |
| ▸ | IDO1 | P14902 | 7/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129809 | 0.84 | TOP2A (0.43) | MAPTKDM4EL3MBTL1RAB9ATDO2 | |
| SCHEMBL20151894 | 0.83 | ALDH1A1 (0.44) | MAPTKDM4ETDO2IDO1TOP2A | |
| SCHEMBL25895953 | 0.82 | TDO2 (0.39) | MAPTKDM4EL3MBTL1RAB9ATDO2 | |
| SCHEMBL23869696 | 0.80 | MAPT (0.38) | MAPTKDM4EL3MBTL1RAB9ATDO2 | |
| SCHEMBL25132524 | 0.79 | TOP2A (0.43) | MAPTKDM4EL3MBTL1RAB9ATDO2 | |
| SCHEMBL20151895 | 0.78 | ALDH1A1 (0.44) | MAPTKDM4ETDO2IDO1TOP2A | |
| SCHEMBL18122193 | 0.77 | TOP2A (0.56) | TDO2IDO1TOP2AMAPK1HTT | |
| SCHEMBL25603214 | 0.76 | ALDH1A1 (0.43) | MAPTKDM4ERAB9ATOP2AALDH1A1 | |
| SCHEMBL22643744 | 0.74 | SLC9A1 (0.35) | TDO2IDO1TOP2AALDH1A1MAPK1 | |
| SCHEMBL25132883 | 0.74 | TTR (0.45) | MAPTRAB9ATDO2IDO1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250181-A1 | MODIFIED CHECKPOINT INHIBITORS AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250181-A1 | MODIFIED CHECKPOINT INHIBITORS AND USES THEREOF | PDCD1, CD274, PDCD1LG2 | MAPT 2852/4885KDM4E 2946/4885L3MBTL1 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.