SCHEMBL20152386

SCHEMBL20152386

c1ccc(C2(c3ccccc3)c3ccccc3N(c3cccc(-c4cccc(N5c6ccccc6[Si](c6ccccc6)(c6ccccc6)c6ccccc65)c4)c3)c3ccccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
ATM Q13315 1/20 0.35
MGLL Q99685 1/20 0.35
ADAMTS5 Q9UNA0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152390 0.99 FAAH (0.35) FAAHALDH1A1HSP90AA1PKMHTT
SCHEMBL20383370 0.96 FAAH (0.33) FAAHALDH1A1HSP90AA1PKMHTT
SCHEMBL20152415 0.95 FAAH (0.35) FAAHALDH1A1HSP90AA1PKMHTT
SCHEMBL20152413 0.95 FAAH (0.35) FAAHALDH1A1HSP90AA1PKMHTT
SCHEMBL20152383 0.94
SCHEMBL20152389 0.92 MGLL (0.30) MGLL
SCHEMBL20383367 0.91
SCHEMBL20383366 0.91
SCHEMBL20152419 0.90 PDE6D (0.32) FAAHMGLL
SCHEMBL20152395 0.90 ITGB2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10673000-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-02 US disclosed
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME ODC1, KCNC1, KCNH1 FAAH 1043/4885ALDH1A1 93/4885HSP90AA1 4457/4885
US-10673000-B2 Heterocyclic compound and organic electroluminescence device including the same ODC1, KCNC1, KCNH1 FAAH 1043/4885ALDH1A1 93/4885HSP90AA1 4457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.