Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153008 | 0.88 | BACE1 (0.44) | NPSR1IAPPTRPV1FFAR1FFAR4 | |
| SCHEMBL20152941 | 0.85 | NPSR1 (0.47) | LTB4RLTB4R2NPSR1PTGS1IAPP | |
| SCHEMBL20153011 | 0.85 | IAPP (0.40) | NPSR1IAPPTRPV1GPR35FFAR1 | |
| SCHEMBL20152937 | 0.76 | LTB4R (0.38) | LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL27643697 | 0.76 | NPSR1 (0.46) | NPSR1PTGS1PTGS2IAPPFFAR1 | |
| SCHEMBL21363228 | 0.73 | ALOX15 (0.48) | NPSR1PTGS1PTGS2GPR35 | |
| SCHEMBL27647753 | 0.72 | CA3 (0.45) | IAPPSLC5A1SLC5A2 | |
| SCHEMBL20153033 | 0.71 | NPSR1 (0.48) | NPSR1IAPPTRPV1 | |
| SCHEMBL19067821 | 0.70 | ALOX15 (0.54) | NPSR1PTGS1PTGS2 | |
| SCHEMBL3698568 | 0.68 | IAPP (0.61) | LTB4RLTB4R2IAPPBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |