Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153484 | 0.79 | CTSA (0.40) | FFAR1OXTRCTSAFBP1 | |
| SCHEMBL4805423 | 0.66 | OXTR (0.46) | FFAR1OXTRKMT2AMEN1MAPT | |
| SCHEMBL16762977 | 0.65 | LMNA (0.42) | OXTRKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL19965687 | 0.64 | NNMT (0.41) | OXTRHRH1KMT2AMEN1MAPT | |
| SCHEMBL18228247 | 0.64 | NNMT (0.47) | OXTRKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1581887 | 0.63 | NNMT (0.46) | OXTRHRH1KMT2AMEN1MAPT | |
| SCHEMBL30108570 | 0.63 | NNMT (0.46) | OXTRHRH1KMT2AMEN1MAPT | |
| SCHEMBL12387805 | 0.63 | FYN (0.40) | OXTRKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10352342 | 0.62 | OXTR (0.45) | FFAR1OXTRKMT2AMEN1MAPT | |
| SCHEMBL22031521 | 0.62 | NNMT (0.42) | OXTRKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089353-A1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |