Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 13/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140402 | 0.84 | CTSA (0.41) | CTSAFFAR1OXTRITGB3ITGAV | |
| SCHEMBL20153474 | 0.82 | CTSA (0.58) | CTSA | |
| SCHEMBL21311667 | 0.81 | ITGB3 (0.37) | CTSAOXTRITGB3ITGAV | |
| SCHEMBL20153487 | 0.80 | ITGB3 (0.37) | CTSAOXTRITGB3ITGAV | |
| SCHEMBL20153486 | 0.80 | CTSA (0.35) | CTSAFFAR1OXTRITGB3ITGAV | |
| SCHEMBL20153477 | 0.79 | FFAR1 (0.36) | CTSAFFAR1OXTRFBP1 | |
| SCHEMBL20139591 | 0.77 | FGFR2 (0.36) | CTSAFFAR1OXTRITGB3ITGAV | |
| SCHEMBL21311525 | 0.76 | OXTR (0.38) | CTSAFFAR1OXTRITGB3ITGAV | |
| SCHEMBL20153392 | 0.75 | NNMT (0.43) | FFAR1OXTRRAB9A | |
| SCHEMBL6106081 | 0.75 | NNMT (0.43) | FFAR1OXTRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2018089353-A1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |