Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743882 | 0.81 | GPR84 (0.39) | GPR84ATMNCEH1ALDH1A1KDM4E | |
| SCHEMBL16983222 | 0.79 | GPR84 (0.45) | GPR84ATMALDH1A1KDM4EMAPT | |
| SCHEMBL31746087 | 0.77 | HTR2A (0.47) | GPR84ATMNCEH1ALDH1A1KDM4E | |
| SCHEMBL19590666 | 0.77 | SIGMAR1 (0.36) | NCEH1ALDH1A1MAPTHTR2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6903453 | 0.76 | SIGMAR1 (0.35) | NCEH1ALDH1A1KDM4EMAPTHTR2A | |
| SCHEMBL10535799 | 0.76 | HTT (0.42) | ALDH1A1MAPT | |
| SCHEMBL5457450 | 0.75 | NCEH1 (0.46) | ATMNCEH1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL15958600 | 0.75 | CYP2D6 (0.41) | GPR84ATMNCEH1ALDH1A1KDM4E | |
| SCHEMBL24924404 | 0.74 | HTR2A (0.35) | NCEH1HTR2A | |
| SCHEMBL3892477 | 0.74 | HTR2A (0.42) | GPR84ATMNCEH1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | UNIV ARIZONA STATE (US) | 2023-08-10 | — | — | US | disclosed |
| US-10944064-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-09 | — | — | US | disclosed |
| US-10836785-B2 | Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-10790457-B2 | Metal-assisted delayed fluorescent emitters containing tridentate ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180148464-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-31 | — | — | US | disclosed |
| US-20180138428-A1 | METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836785-B2 | Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues | PAICS, DNTT, PNPO | GPR84 1087/4885ATM 3384/4885NCEH1 4338/4885 |
| US-10944064-B2 | Tetradentate metal complexes with carbon group bridging ligands | STAU1, POLR1G, CLTC | GPR84 2055/4885ATM 3123/4885NCEH1 4882/4885 |
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | STAU1, POLR1G, CLTC | GPR84 2055/4885ATM 3123/4885NCEH1 4882/4885 |
| US-20180138428-A1 | METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS | SLC30A6, SLC30A5, BRI3BP | GPR84 700/4885ATM 1987/4885NCEH1 4875/4885 |
| US-10790457-B2 | Metal-assisted delayed fluorescent emitters containing tridentate ligands | SLC30A6, SLC30A5, BRI3BP | GPR84 700/4885ATM 1987/4885NCEH1 4875/4885 |
| US-20180148464-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | PAICS, DNTT, PNPO | GPR84 1087/4885ATM 3384/4885NCEH1 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.