SCHEMBL20153677

SCHEMBL20153677

CCc1c2ccccc2c(C)n1N

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
CYP1A2 P05177 2/20 0.32
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.31
NR4A3 Q92570 1/20 0.31
MYC P01106 1/20 0.31
ALDH1A1 P00352 5/20 0.31
HSD17B10 Q99714 3/20 0.31
HPGD P15428 2/20 0.31
NUDT1 P36639 1/20 0.31
LMNA P02545 2/20 0.30
TSHR P16473 2/20 0.30
KMT2A Q03164 4/20 0.30
HTT P42858 4/20 0.30
MEN1 O00255 2/20 0.30
MAPT P10636 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
NSD2 O96028 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24924297 0.87 TP53 (0.36) KDM4ECYP1A2ATMSMN1; SMN2TP53
SCHEMBL9927339 0.79 CYP1A2 (0.43) KDM4ECYP1A2SMN1; SMN2MYCALDH1A1
SCHEMBL11716790 0.77 GPR3 (0.39) KDM4ECYP1A2SMN1; SMN2TP53ALDH1A1
SCHEMBL11722314 0.75 ALDH1A1 (0.42) KDM4ECYP1A2ATMSMN1; SMN2TP53
SCHEMBL20153656 0.75 CYP2D6 (0.33) SMN1; SMN2HSD17B10TSHRTDP1
SCHEMBL11718010 0.72 CNR2 (0.41) KDM4ECYP1A2ALDH1A1HPGDLMNA
SCHEMBL11719558 0.71 CNR2 (0.37) SMN1; SMN2ALDH1A1LMNAKMT2AMEN1
SCHEMBL11726453 0.70 GPR3 (0.46) KDM4ECYP1A2SMN1; SMN2TP53NR4A3
SCHEMBL11718811 0.69 LMNA (0.50) KDM4EATMSMN1; SMN2ALDH1A1LMNA
SCHEMBL11714129 0.69 TDP1 (0.51) KDM4EALDH1A1HPGDLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180138428-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138428-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS SLC30A6, SLC30A5, BRI3BP KDM4E 4862/4885CYP1A2 4243/4885ATM 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.