Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1E | P28566 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610991 | 0.82 | KDM4E (0.34) | CYP2D6TSHRSMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL24924297 | 0.82 | TP53 (0.36) | CYP2D6TSHRSMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL23046376 | 0.78 | HTR2A (0.34) | HTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL23229479 | 0.77 | NPC1 (0.37) | SLC6A2HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL24924405 | 0.75 | KDM4E (0.34) | SMN1; SMN2TDP1 | |
| SCHEMBL20153677 | 0.75 | KDM4E (0.34) | TSHRSMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL23710821 | 0.71 | ALDH1A1 (0.36) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL25971764 | 0.70 | — | — | |
| SCHEMBL11726453 | 0.66 | GPR3 (0.46) | CYP2D6CYP2A6TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL11719930 | 0.63 | POLB (0.44) | SLC6A4TSHRHSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11653560-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-20210126208-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | UNIV ARIZONA STATE (US) | 2021-04-29 | — | — | US | disclosed |
| US-10944064-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-09 | — | — | US | disclosed |
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20210024559-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | UNIV ARIZONA STATE (US) | 2021-01-28 | — | — | US | disclosed |
| US-10790457-B2 | Metal-assisted delayed fluorescent emitters containing tridentate ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180138428-A1 | METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210126208-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | STAU1, POLR1G, CLTC | CYP2D6 4806/4885SLC6A2 1812/4885TAAR1 768/4885 |
| US-10944064-B2 | Tetradentate metal complexes with carbon group bridging ligands | STAU1, POLR1G, CLTC | CYP2D6 4806/4885SLC6A2 1812/4885TAAR1 768/4885 |
| US-11653560-B2 | Tetradentate metal complexes with carbon group bridging ligands | PDCD2L, STAU1, POLR1G | CYP2D6 3847/4885SLC6A2 1632/4885TAAR1 972/4885 |
| US-20180138428-A1 | METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS | SLC30A6, SLC30A5, BRI3BP | CYP2D6 4586/4885SLC6A2 1139/4885TAAR1 77/4885 |
| US-10790457-B2 | Metal-assisted delayed fluorescent emitters containing tridentate ligands | SLC30A6, SLC30A5, BRI3BP | CYP2D6 4586/4885SLC6A2 1139/4885TAAR1 77/4885 |
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | PDCD1, PDCD11, TYMP | CYP2D6 1691/4885SLC6A2 2425/4885TAAR1 1864/4885 |
| US-20210024559-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | PAICS, DNTT, PNPO | CYP2D6 3071/4885SLC6A2 3683/4885TAAR1 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.