SCHEMBL2015384

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2015572	0.89	DRD2 (0.41)	SOS1DRD2ADRA2APIK3CDHTR2A
	SCHEMBL2020083	0.83	DRD3 (0.40)	SOS1DRD2AVPR1AADRA2ACYP2D6
	SCHEMBL2016220	0.79	SOS1 (0.41)	SOS1DRD2ADRA2AHTR2ALMNA
	SCHEMBL696852	0.79	SOS1 (0.41)	SOS1DRD2ADRA2AHTR2ALMNA
	SCHEMBL2019235	0.77	HTR2C (0.52)	HTR2AHTR2CHTR2B
	SCHEMBL2015836	0.77	HTR2C (0.52)	HTR2AHTR2CHTR2B
	SCHEMBL2014411	0.76	SOS1 (0.39)	SOS1DRD2AVPR1ACYP2D6CYP2C9
	SCHEMBL20328102	0.73	AVPR1A (0.41)	DRD2AVPR1APIK3CDPIK3CBPIK3CG
	SCHEMBL30962043	0.73	SCN9A (0.44)	AVPR1APIK3CDPIK3CBPIK3CGHTR2C
	SCHEMBL2565554	0.73	DRD2 (0.44)	SOS1DRD2ADRA2AHTR2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.