SCHEMBL2016220

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL696852	1.00	SOS1 (0.41)	SOS1DRD2NOTUMHTR2ALMNA
	SCHEMBL2014414	0.82	DRD2 (0.44)	DRD2NOTUMLMNAKMT2AHTR1A
	SCHEMBL2016209	0.82	SOS1 (0.46)	SOS1NOTUMTP53TSHRAGTR2
	SCHEMBL2017678	0.81	SOS1 (0.41)	SOS1DRD2HTR2ALMNAHTR2C
	SCHEMBL2566784	0.81	SOS1 (0.41)	SOS1DRD2HTR2ALMNAHTR2C
	SCHEMBL2017960	0.81	ADRA1B (0.45)	SOS1CYP2D6CYP2C9HTR1AADRA1D
	SCHEMBL2019939	0.81	ADRA1B (0.45)	SOS1CYP2D6CYP2C9HTR1AADRA1D
	SCHEMBL2018737	0.81	SOS1 (0.41)	SOS1DRD2HTR2ALMNAHTR2C
	SCHEMBL2015384	0.79	SOS1 (0.42)	SOS1DRD2HTR2ALMNAHTR2C
	SCHEMBL2015572	0.79	DRD2 (0.41)	SOS1DRD2HTR2ALMNAHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.