SCHEMBL201542

SCHEMBL201542

N=C(NO)c1ccc2c(c1)OCO2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPK1 P28482 1/20 0.55
RAB9A P51151 8/20 0.50
NPC1 O15118 7/20 0.50
SMN1; SMN2 Q16637 6/20 0.50
MAPT P10636 4/20 0.50
NFKB1 P19838 3/20 0.50
NFKB2 Q00653 3/20 0.50
RELA Q04206 3/20 0.50
PKM P14618 2/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CASP3 P42574 3/20 0.49
SENP7 Q9BQF6 3/20 0.49
PTGS2 P35354 1/20 0.49
SRD5A2 P31213 1/20 0.49
GAA P10253 1/20 0.48
CYP3A4 P08684 1/20 0.47
HPGD P15428 3/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18359200 0.78 NPC1 (0.68) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL2968032 0.77 PLAU (0.58) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
Hydrochloric Acid SCHEMBL3102294 0.76 PLAU (0.57) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL16697633 0.74 ALDH1A1 (0.50) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL6328340 0.74 PRKCI (0.58) RAB9ANPC1MAPT
SCHEMBL5787334 0.73 ALDH1A1 (0.69) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL29723925 0.73 ALDH1A1 (0.53) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL4354695 0.72 ALDH1A1 (0.62) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL2601929 0.72 ALDH1A1 (0.74) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL4824941 0.72 SRD5A2 (0.82) ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350903-B Anti-corrosion fireproof sandwich structure coating for nuclear island and preparation method and application thereof 大厂金隅涂料有限责任公司 2025-05-13 CN claimed
CN-119350903-A Anti-corrosion fireproof sandwich structure coating for nuclear island and preparation method and application thereof 大厂金隅涂料有限责任公司 2025-01-24 CN claimed
US-11932632-B1 N'-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzo[d][1,3]dioxole-5 carboximidamide as an antimicrobial compound King Faisal University (SA) 2024-03-19 US claimed
US-11926621-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzo[d][1,3]dioxole-5-carboximidamide as an antimicrobial compound King Faisal University (SA) 2024-03-12 US claimed
EP-3634403-B1 PHENYL-HETEROCYCLE-PHENYL DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF MELANOMA MAX PLANCK GESELLSCHAFT (DE) 2025-06-25 EP disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
CN-119350903-B Anti-corrosion fireproof sandwich structure coating for nuclear island and preparation method and application thereof 大厂金隅涂料有限责任公司 2025-05-13 CN disclosed
CN-119350903-A Anti-corrosion fireproof sandwich structure coating for nuclear island and preparation method and application thereof 大厂金隅涂料有限责任公司 2025-01-24 CN disclosed
US-11932632-B1 N'-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzo[d][1,3]dioxole-5 carboximidamide as an antimicrobial compound King Faisal University (SA) 2024-03-19 US disclosed
US-11926621-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzo[d][1,3]dioxole-5-carboximidamide as an antimicrobial compound King Faisal University (SA) 2024-03-12 US disclosed
US-11180518-B2 Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-11-23 US disclosed
US-20200165279-A1 PHENYL-HETEROCYCLE-PHENYL DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF MELANOMA MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-05-28 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
EP-1996180-A1 ANTIBACTERIAL AGENTS Prolysis Limited (GB) 2008-12-03 EP disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed
US-6924284-B2 PARP inhibitors ICOS CORPORATION (US) 2005-08-02 US disclosed
EP-1373264-B1 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-22 EP disclosed
US-6821972-B2 ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS PFIZER INC. 2004-11-23 US disclosed
US-20040087588-A1 Parp inhibitors ICOS CORPORATION 2004-05-06 US disclosed
US-20030069291-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors PFIZER INC. 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11926621-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzo[d][1,3]dioxole-5-carboximidamide as an antimicrobial compound NOD1, AADAC, DAO ALDH1A1 913/4885MAPK1 2398/4885RAB9A 3550/4885
US-20040087588-A1 Parp inhibitors PARP1, PARP2, PARP11 ALDH1A1 338/4885MAPK1 922/4885RAB9A 4452/4885
US-20200165279-A1 PHENYL-HETEROCYCLE-PHENYL DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF MELANOMA TYR, MITF, VHL ALDH1A1 32/4885MAPK1 1540/4885RAB9A 2195/4885
US-11180518-B2 Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma TYR, MITF, VHL ALDH1A1 32/4885MAPK1 1540/4885RAB9A 2195/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 ALDH1A1 800/4885MAPK1 419/4885RAB9A 2799/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 ALDH1A1 800/4885MAPK1 419/4885RAB9A 2799/4885
US-11932632-B1 N'-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzo[d][1,3]dioxole-5 carboximidamide as an antimicrobial compound NOD1, AADAC, DAO ALDH1A1 910/4885MAPK1 1867/4885RAB9A 3927/4885
US-20030069291-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors PAH, CYP2F1, CYP7A1 ALDH1A1 376/4885MAPK1 1221/4885RAB9A 1744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.