Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155046 | 0.81 | CREBBP (0.30) | CREBBP | |
| SCHEMBL20155536 | 0.80 | KDM4E (0.37) | — | |
| SCHEMBL20155722 | 0.77 | EGFR (0.39) | — | |
| SCHEMBL20155435 | 0.74 | KDR (0.35) | — | |
| SCHEMBL20155547 | 0.72 | MAPT (0.40) | — | |
| SCHEMBL30937519 | 0.71 | ATR (0.37) | — | |
| SCHEMBL20155151 | 0.71 | — | — | |
| SCHEMBL529516 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL30937638 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL20155717 | 0.67 | ERN1 (0.33) | MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |