Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155114 | 0.80 | MAPT (0.36) | MAPTKDM4ETHRBTDP1L3MBTL1 | |
| SCHEMBL20155576 | 0.79 | RET (0.42) | TDP1L3MBTL1SMN1; SMN2POLBGAA | |
| SCHEMBL20155536 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL20155142 | 0.72 | CREBBP (0.32) | — | |
| SCHEMBL10688866 | 0.71 | MAPT (0.49) | MAPTKDM4ETHRBTDP1L3MBTL1 | |
| SCHEMBL13197243 | 0.69 | G6PC1 (0.58) | MAPTKDM4ETHRBTDP1ALDH1A1 | |
| SCHEMBL34460869 | 0.69 | G6PC1 (0.58) | MAPTKDM4ETHRBTDP1ALDH1A1 | |
| SCHEMBL20155722 | 0.69 | EGFR (0.39) | — | |
| SCHEMBL20155435 | 0.69 | KDR (0.35) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL529516 | 0.68 | ALDH1A1 (0.38) | MAPTKDM4ETHRBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |