Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.43 |
| ▸ | MAT2A | P31153 | 9/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155116 | 0.91 | BRD4 (0.45) | BRD4MAT2A | |
| SCHEMBL20155737 | 0.89 | BRD4 (0.47) | BRD4MAT2A | |
| SCHEMBL20155184 | 0.86 | BRD4 (0.40) | BRD4MAT2ATGFBR1 | |
| SCHEMBL20155169 | 0.85 | BRD4 (0.46) | BRD4MAT2ABRD2BRD3 | |
| SCHEMBL20155728 | 0.83 | BRD4 (0.43) | BRD4TGFBR1 | |
| SCHEMBL20155659 | 0.81 | BRD4 (0.46) | BRD4BRD2CREBBP | |
| SCHEMBL20155427 | 0.79 | BRD4 (0.48) | BRD4 | |
| SCHEMBL20155652 | 0.78 | BRD4 (0.48) | BRD4MAT2ABRD2BRD3 | |
| SCHEMBL20155185 | 0.76 | BRD4 (0.42) | BRD4MAT2A | |
| SCHEMBL20155628 | 0.76 | BRD4 (0.47) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |