SCHEMBL2015524

SCHEMBL2015524

Nc1cc(CO)nc(CO)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
CHRM1 P11229 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
ADRA1B P35368 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
CCR1 P32246 1/20 0.39
KCNH2 Q12809 1/20 0.36
ACHE P22303 1/20 0.32
PIK3CA P42336 1/20 0.32
PI4KA P42356 1/20 0.32
PI4KB Q9UBF8 1/20 0.32
TOP2A P11388 1/20 0.32
TOP2B Q02880 1/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26241406 0.89 NOS3 (0.45) GRIN2DGRIN3BCHRM1ADRA1DADRA1A
SCHEMBL5865335 0.84 GRIN2D (0.39) GRIN2DGRIN3BCHRM1ADRA1DADRA1A
SCHEMBL31042999 0.84 GRIN2D (0.39) GRIN2DGRIN3BCHRM1ADRA1DADRA1A
SCHEMBL22556943 0.84 GRIN2D (0.39) GRIN2DGRIN3BCHRM1ADRA1DADRA1A
SCHEMBL9023790 0.77 CCR1 (0.42) CCR1ACHEPIK3CAPI4KAPI4KB
SCHEMBL4270536 0.74 ACHE (0.52) CCR1ACHEALDH1A1KDM4EHPGD
SCHEMBL2014831 0.72 SMN1; SMN2 (0.39) KCNH2ALDH1A1KDM4ETHRBASIC3
SCHEMBL14721449 0.72 CCR1 (0.39) CCR1ACHEALDH1A1KDM4EHPGD
SCHEMBL7274937 0.72 NOS2 (0.54) GRIN2DGRIN3BCHRM1ADRA1DADRA1A
SCHEMBL12161257 0.72 NOS2 (0.43) CCR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119242161-A Preparation method of plastic runway glue solution and plastic runway 湖北金五环体育设施有限公司 2025-01-03 CN claimed
CN-119242161-A Preparation method of plastic runway glue solution and plastic runway 湖北金五环体育设施有限公司 2025-01-03 CN disclosed
US-9486544-B2 Manganese chelates and their use as contrast agents in magnetic resonance imaging (MRI) GE HEALTHCARE AS (NO) 2016-11-08 US disclosed
US-9486544-B2 Manganese chelates and their use as contrast agents in magnetic resonance imaging (MRI) GE HEALTHCARE AS (NO) 2016-11-08 US disclosed
US-9486544-B2 Manganese chelates and their use as contrast agents in magnetic resonance imaging (MRI) GE HEALTHCARE AS (NO) 2016-11-08 US disclosed
EP-2512524-B1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2016-10-05 EP disclosed
EP-2512524-B1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2016-10-05 EP disclosed
EP-2512524-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE Healthcare AS (NO) 2012-10-24 EP disclosed
US-20120244081-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2012-09-27 US disclosed
US-20120244081-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2012-09-27 US disclosed
US-20120244081-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2012-09-27 US disclosed
WO-2011073371-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2011-06-23 WO disclosed
WO-2011073371-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120244081-A1 MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) MAG, MPI, MB GRIN2D 2118/4885GRIN3B 397/4885CHRM1 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.