Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491178 | 0.89 | BCL2 (0.47) | BCL2PIK3CDTAAR1HTR2AMPO | |
| SCHEMBL2012746 | 0.88 | PIK3CD (0.35) | BCL2PIK3CD | |
| Trifluoroacetic Acid SCHEMBL2012078 | 0.81 | BCL2 (0.41) | BCL2PIK3CDTAAR1 | |
| SCHEMBL12403232 | 0.79 | BCL2 (0.48) | BCL2PIK3CDTAAR1MPO | |
| SCHEMBL2016433 | 0.78 | TAAR1 (0.43) | BCL2PIK3CDTAAR1HTR2AMPO | |
| SCHEMBL2019261 | 0.77 | PIK3CD (0.44) | BCL2PIK3CD | |
| SCHEMBL2012486 | 0.76 | PIK3CD (0.46) | BCL2PIK3CDTAAR1 | |
| SCHEMBL2015596 | 0.75 | BCL2 (0.48) | BCL2PIK3CD | |
| SCHEMBL2015779 | 0.73 | PIK3CD (0.44) | PIK3CDTAAR1 | |
| SCHEMBL2012742 | 0.72 | PIK3CD (0.46) | BCL2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |