Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668023 | 0.81 | VNN1 (0.39) | VNN1ALDH1A1HPGDMAOAMAOB | |
| SCHEMBL23715349 | 0.80 | TSHR (0.42) | VNN1TSHRALDH1A1HPGDSLC22A12 | |
| SCHEMBL20686837 | 0.77 | PRSS1 (0.47) | ALDH1A1HPGDMAOAMAOBMAPT | |
| SCHEMBL20156488 | 0.77 | L3MBTL1 (0.36) | TSHRALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL16956258 | 0.76 | TSHR (0.45) | VNN1TSHRALDH1A1HPGDSLC22A12 | |
| SCHEMBL21698571 | 0.74 | AKR1B1 (0.34) | — | |
| SCHEMBL16953414 | 0.74 | VNN1 (0.40) | VNN1TSHRALDH1A1HPGDSLC22A12 | |
| SCHEMBL20836577 | 0.73 | TDP1 (0.55) | TSHRALDH1A1HPGDMAOAMAOB | |
| SCHEMBL31186416 | 0.73 | ALDH1A1 (0.51) | VNN1TSHRALDH1A1HPGDTDP1 | |
| SCHEMBL23967561 | 0.73 | HDAC1 (0.49) | ALDH1A1MAOAMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |