Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156555 | 0.83 | FLT1 (0.48) | FLT1FLT4KDRPOLBTHRB | |
| SCHEMBL10290473 | 0.82 | HSD17B1 (0.56) | FLT1FLT4KDRPOLBTHRB | |
| SCHEMBL29483331 | 0.80 | HSD17B1 (0.41) | POLBTHRBMEN1KMT2AHPGD | |
| SCHEMBL20262941 | 0.80 | HSD17B1 (0.41) | POLBTHRBMEN1KMT2AHPGD | |
| SCHEMBL7909295 | 0.78 | HSD17B1 (0.51) | HTTALDH1A1KDM4EHSD17B1TSHR | |
| SCHEMBL27005987 | 0.78 | HSD17B1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL1363368 | 0.78 | TRPA1 (0.42) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL1548854 | 0.78 | SMN1; SMN2 (0.59) | FLT1FLT4KDRPOLBTHRB | |
| SCHEMBL7932090 | 0.78 | HSD17B1 (0.37) | FLT1FLT4KDRMAPTKMT2A | |
| Ethane SCHEMBL7194508 | 0.77 | SMN1; SMN2 (0.57) | FLT1FLT4KDRPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |