Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23368569 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL22627609 | 0.69 | — | — | |
| SCHEMBL6888587 | 0.67 | — | — | |
| SCHEMBL26080985 | 0.67 | MMP1 (0.32) | ALDH1A1 | |
| SCHEMBL18752103 | 0.67 | — | — | |
| SCHEMBL22620589 | 0.67 | MMP1 (0.32) | ALDH1A1 | |
| SCHEMBL17629228 | 0.66 | ALOX5 (0.47) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL15944417 | 0.66 | ALOX5 (0.47) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL25489485 | 0.65 | — | — | |
| SCHEMBL21646485 | 0.64 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |