Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL20141711 | 0.88 | HTR2C (0.39) | ALDH1A1LMNAHTR2CHRH4PRKCQ | |
| SCHEMBL3297385 | 0.79 | HTR6 (0.57) | ALDH1A1LMNAHTR2CHTR6ADRB1 | |
| SCHEMBL20141437 | 0.78 | HTR1A (0.44) | ALDH1A1LMNAHTR2CPRKCQPRKCD | |
| SCHEMBL20141435 | 0.78 | HTR1A (0.44) | ALDH1A1LMNAHTR2CPRKCQPRKCD | |
| SCHEMBL4244450 | 0.78 | HTR6 (0.61) | ALDH1A1LMNAHTR2CHRH4PRKCQ | |
| SCHEMBL4247868 | 0.78 | HTR6 (0.61) | ALDH1A1LMNAHTR2CHRH4PRKCQ | |
| SCHEMBL4244446 | 0.78 | HTR6 (0.61) | ALDH1A1LMNAHTR2CHRH4PRKCQ | |
| SCHEMBL30146614 | 0.77 | ADRB1 (0.64) | HTR2CHTR6ADRB1HTR1AMAPT | |
| SCHEMBL4247455 | 0.76 | MKNK1 (0.39) | ALDH1A1LMNAHTR2CPRKCQPRKCD | |
| SCHEMBL4246453 | 0.76 | MKNK1 (0.39) | ALDH1A1LMNAHTR2CPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |