Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141435 | 1.00 | HTR1A (0.44) | HTR1AROCK2ROCK1PRKCQPRKCD | |
| SCHEMBL20140658 | 0.78 | ROCK2 (0.50) | ROCK2ROCK1PRKCQPRKCDPRKCI | |
| SCHEMBL30146781 | 0.78 | ROCK2 (0.43) | ROCK2ROCK1PRKCQPRKCDNOS1 | |
| SCHEMBL20140662 | 0.78 | ROCK2 (0.50) | ROCK2ROCK1PRKCQPRKCDPRKCI | |
| SCHEMBL20156942 | 0.78 | ALDH1A1 (0.40) | HTR1APRKCQPRKCDALDH1A1LMNA | |
| SCHEMBL4247868 | 0.76 | HTR6 (0.61) | HTR1APRKCQPRKCDALDH1A1LMNA | |
| SCHEMBL4244450 | 0.76 | HTR6 (0.61) | HTR1APRKCQPRKCDALDH1A1LMNA | |
| SCHEMBL4244446 | 0.76 | HTR6 (0.61) | HTR1APRKCQPRKCDALDH1A1LMNA | |
| SCHEMBL27630897 | 0.76 | HTR1A (0.51) | HTR1ANOS1CYP3A4PRKCZHTR2C | |
| SCHEMBL20140653 | 0.75 | PIM1 (0.41) | ROCK2PRKCQPRKCDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |