Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | HTR7 | P34969 | 7/20 | 0.49 |
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898671 | 0.87 | MC4R (0.51) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL3088832 | 0.82 | DRD4 (0.54) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL20156862 | 0.81 | DRD2 (0.45) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL429372 | 0.79 | DRD4 (0.47) | DRD2HTR1AHTR7DRD4HSP90AB1 | |
| SCHEMBL9118895 | 0.78 | DRD2 (0.45) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL2077261 | 0.78 | ADRA2C (0.56) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL20156847 | 0.78 | DRD4 (0.51) | DRD2HTR1ADRD4DRD3GRM5 | |
| SCHEMBL20157270 | 0.76 | DRD2 (0.54) | DRD2HTR1AHTR7DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL1483325 | 0.76 | ADRA2C (0.55) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL829177 | 0.75 | AR (0.65) | DRD2HTR1ADRD4GRM5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |