Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898671 | 0.84 | MC4R (0.51) | DRD2HTR2AHRH1HTR7HTR1A | |
| SCHEMBL20156961 | 0.81 | DRD2 (0.49) | DRD2HTR2AHTR7HTR1AMC4R | |
| SCHEMBL3088832 | 0.80 | DRD4 (0.54) | DRD2HTR7HTR1ADRD4GRM5 | |
| SCHEMBL20156977 | 0.78 | HTR7 (0.47) | DRD2HTR2AHTR7HTR1ATHRB | |
| SCHEMBL2077261 | 0.75 | ADRA2C (0.56) | DRD2HTR2AHTR7HTR1ADRD4 | |
| SCHEMBL31664662 | 0.75 | HTR7 (0.41) | DRD2HTR2AHTR7HTR1ATHRB | |
| SCHEMBL12132217 | 0.74 | DRD2 (0.39) | DRD2HTR2AHTR7HTR1ATHRB | |
| SCHEMBL20157270 | 0.74 | DRD2 (0.54) | DRD2HTR2AHTR7HTR1AHSP90AB1 | |
| Hydrochloric Acid SCHEMBL1483325 | 0.74 | ADRA2C (0.55) | DRD2HTR2AHTR7HTR1ADRD4 | |
| SCHEMBL20157218 | 0.73 | HTR7 (0.40) | DRD2HTR2AHRH1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |