Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141285 | 0.93 | KDM4E (0.40) | KDM4EKMT2ADRD4DRD3DRD2 | |
| SCHEMBL20140571 | 0.83 | DRD4 (0.39) | KDM4EDRD4DRD3DRD2ALDH1A1 | |
| SCHEMBL20156864 | 0.74 | MTOR (0.47) | KMT2AALDH1A1P2RX7HTTSMN1; SMN2 | |
| SCHEMBL20140384 | 0.71 | MALT1 (0.41) | P2RX7 | |
| SCHEMBL20140506 | 0.71 | CHRM2 (0.43) | KMT2AP2RX7MTORRPTORMLST8 | |
| SCHEMBL20140508 | 0.71 | CHRM2 (0.43) | KMT2AP2RX7MTORRPTORMLST8 | |
| SCHEMBL20140513 | 0.68 | DRD4 (0.41) | KDM4EKMT2ADRD4DRD3DRD2 | |
| SCHEMBL20157267 | 0.68 | DRD4 (0.52) | KDM4EDRD4DRD3DRD2ALDH1A1 | |
| SCHEMBL22187910 | 0.67 | MTOR (0.45) | KDM4EDRD4DRD3ALDH1A1MTOR | |
| SCHEMBL20157237 | 0.67 | DRD4 (0.44) | KDM4EKMT2ADRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |