Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD4 | P21917 | 6/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088832 | 0.85 | DRD4 (0.54) | HTR7PHGDHDRD2DRD4GRM5 | |
| SCHEMBL2077261 | 0.80 | ADRA2C (0.56) | HTR7DRD2DRD4GRM5DRD3 | |
| Hydrochloric Acid SCHEMBL1483325 | 0.79 | ADRA2C (0.55) | HTR7DRD2DRD4GRM5DRD3 | |
| SCHEMBL20156862 | 0.78 | DRD2 (0.45) | HTR7THRBDRD2DRD4GRM5 | |
| SCHEMBL829177 | 0.77 | AR (0.65) | DRD2DRD4GRM5HTR1AAR | |
| SCHEMBL30406641 | 0.77 | AR (0.59) | DRD2DRD4GRM5DRD3HTR1A | |
| SCHEMBL2321072 | 0.77 | DRD4 (0.49) | HTR7PHGDHDRD2DRD4GRM5 | |
| SCHEMBL12126933 | 0.77 | DRD2 (0.43) | HTR7THRBDRD2DRD4GRM5 | |
| SCHEMBL23277098 | 0.77 | KDM4E (0.58) | HTR7DRD2DRD4GRM5DRD3 | |
| SCHEMBL21572676 | 0.77 | DRD4 (0.48) | HTR7DRD2DRD4GRM5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |