Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088832 | 0.87 | DRD4 (0.54) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL23277098 | 0.81 | KDM4E (0.58) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL2323797 | 0.79 | ADRB1 (0.55) | DRD4DRD2DRD3HTR1AADRA1A | |
| SCHEMBL829177 | 0.79 | AR (0.65) | DRD4DRD2GRM5HTR1AADRA1A | |
| SCHEMBL30406641 | 0.79 | AR (0.59) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL2321076 | 0.79 | DRD4 (0.49) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL21572676 | 0.78 | DRD4 (0.48) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL20156847 | 0.78 | DRD4 (0.51) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL2077260 | 0.78 | GRM5 (0.51) | DRD4DRD2GRM5DRD3HTR1A | |
| SCHEMBL2077261 | 0.78 | ADRA2C (0.56) | DRD4DRD2GRM5DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |