Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.55 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.55 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.55 |
| ▸ | RET | P07949 | 12/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156964 | 0.88 | MTOR (0.49) | MTORRPTORMLST8RETKDM4E | |
| SCHEMBL20141707 | 0.85 | MTOR (0.47) | MTORRPTORMLST8KDM4EFASN | |
| SCHEMBL20156997 | 0.82 | MTOR (0.44) | MTORRPTORMLST8RETKDM4E | |
| SCHEMBL20156834 | 0.81 | MTOR (0.54) | MTORRPTORMLST8LMNAHTT | |
| SCHEMBL20139980 | 0.80 | MTOR (0.46) | MTORRPTORMLST8RETHCRTR1 | |
| SCHEMBL20140046 | 0.79 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL20140070 | 0.79 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL20140048 | 0.79 | MTOR (0.47) | MTORRPTORMLST8 | |
| SCHEMBL20139934 | 0.78 | PPARG (0.47) | MTORRPTORMLST8RETKDM4E | |
| SCHEMBL20141367 | 0.78 | RET (0.42) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |